Prof. O.A. Ayoka

Professor

PROF. AYOKA OLADELE ABIODUN

AREAS OF SPECIALIZATION: Basic Physiology and Neuro-Physiology

RESEARCH INTEREST: Neuro and Ethno

RANK: Professor

Phone No:    07063014846

E-MAIL ADDRESS: aoayoka@oauife.edu.ng

OFFICE ADDRESS: Room 212

PUBLICATIONS

1. Thesis/ Dissertation

a) The Effects of Aqueous Extract of Momordica charantia on various isolated segments of

Gastrointestinal Tract in Albino Rats (B.Sc. Physiology Dissertation) June, 1987

b) Effect of Calctonin Gne-Related prptide on gastric acid secretion in male Albino Wistar Rats (M.Sc. Thesis)  January, 1990

c) Neuropharmacological effects of Spondias mombin extracts (M. Phil. Thesis)  November, 2003

d) Neural Mechanisms of Some of the Neurotropic Properties of Fractions of Spondias mombin L. (Anacardiaceae) (PhD Thesis)      January, 2009

 

  1. Book/Monographs

 

  1. Authored

Adeoshun I.O., Kukoyi B.I., Ayoka A.O., Akomolafe R.O., Ajayi O.E., Bamitale k.D.S.,

Ogunlade O., Owolabi A. R. and Akinsomisoye O. S. (2012) Physiological Sciences Practical

Manual Edited for the Department of Physiological Sciences and Department of Medical

Pharmacology and Therapeutics, OAU, Ile Ife. Published by Andkolad Publishers Ltd. ISBN 978-45273-0-8

 

3. Edited:             None

 

Published Articles

  • 1) Akomolafe R. O., Adeoshun I. O., Elujoba A. A., Iwalewa E. O. and Ayoka A. O. (2003) “Effects of Cassia sieberiena leaf extracts on the intestinal motility of rat” African Journal of Biomedical Research 6, 141 – 145 (published in Nigeria).
  • 2) Aderibigbe A. O., Wakeel O. K., Ayoka A. O., Adeyemi I. O. and Subiar H. G. (2004) “Effect of an Aqueous Extract of Securidaca longipendunculata in Mice” Journal of Scientific and Industrial Studies 2(1) 83 – 87. (Published in Nigeria).
  • 3) Akomolafe R. O., Adeoshun I. O., Ayoka A. O., Elujoba A. A. and Iwalewa E. O. (2004) “An in vitro study of the effects of Cassia podocarpa fruit on intestinal motility of rats” Pytomedicine 11, 249 – 254 (published in Germany).
  • 4) Ayoka A. O., Akomolafe R. O., Iwalewa E. O. and Ukponmwan O. E. (2005) “Studies on the anxiolytic effects of Spondias mombin (Anacardiaceae) in mice and rats” African Journal of Traditional Complementary and Alternative Medicine 2(2) 153 – 165 (published in Nigeria).
  • 5) Akomolafe R. O., Adeoshun I. O., Fakunle J. B., Iwalewa E. O., Ayoka A. O. and Akanji B. O. (2006) “Changes in the Visceral Function of Plasmodium Berrghei-infected and uninfected rats following administration of Artemether” Clinical and Experimental Pharmacology and Physiology 33, 1180-1183. (Published in Australia).
  • 6) Ayoka A. O., Akomolafe R. O., Iwalewa E. O., Akamu M. A. and Ukponmwan O. E. (2006) “Sedative, antiepileptic and antipsychotic effects of Spondia mombin (Anacardiaceae) in mice and rats” Journal of Ethnopharmacology 103, 166 – 175 (published in Netherlands).
  • 7) Nwoha P. U., Ayoka A., Ibeh J. and Okoro I. (2007) “Adult Malnutrition affects Behaviour of Mice” Journal of Environmental Neuroscience and Biomedicine 1(1), 27 – 33 (published in Nigeria).
  • 8) Ofusori D. A., Oluwayinka O. P., Adelakun A. E., Keji S. T., Oluyemi K. A., Adesanya O. A., Ajeigbe K. O. and Ayoka A. O. (2007) “Evaluation of the effect of ethanolic extract of Croton zambesicus on the testes of Swiss albino mice” African Journal of Biotechnology 6(21), 2434 – 2438 (published in Kenya).
  • 9) Ofusori D.A, Caxton-Martins E.A, Adenowo T.K, Ojo G.B, Falana B.A, Komolafe

A.O, Ayoka A.O, Adeeyo A.O and Oluyemi K.A (2007). “Morphometric Study of the Stomach of African Pangolin Manis tricuspis).” Sci. Res. Essays Vol. 2 (10), pp. 465-467 (published in Kenya).

  • 10) Ofusori D. A., Adelakun A. E., Ayoka O. A., Ibeh J. A., Adeeyo O. A., Adesanya O. A. and Ajeigbe K. O. (2008) “Histological investigation of the effect of Croton zambesicus on the liver of Swiss albino mice.” The Internet Journal of Gastroenterology. Vol. 8(1), 1 -16 (published in Mexico).
  • 11) Ofusori D. A., Adelakun A. E., Ayoka A. O., Olawayinka O. P., Omotosho E. O., Odukoya S. A. and Adeyemi D. O. (2008) “Waterleaf (Talinum tiangulare) Enhances Cerebral Functions in Swiss albino mice” Journal of Neurological Sciences 25(4) 96 – 103 (published in Turkey).
  • 12) Odukoya S. A., Adeeyo O. A., Ofusori D. A., Caxton-Martins A. E., Ayoka A. O.,

Oyewo O. O., Babatunde L. S., Yusuf U. A., Adegoke A. A. and Ishola O. O. (2008) “Histological investigation of the pregnant and non-pregnant uterine limbs of the frugivorous bat (Eidolon helvum) International Journal of Integrative Biology 3(3), 169 -174 (published in Singapore).

  • 13) Ofusori D. A., Ayoka A. O., Adelakun A. E., Falana B. A., Adeeyo O. A., Ajeigbe K. O and Yusuf U. A. (2008) “Microanatomical Effect of ethanolic extract of Garcinia kola

on the lung of Swiss albino mice” The Internet Journal of Pulmonary Medicine 10(1) (published in USA).

  • 14) Ofusori D. A., Josiah S. J., Ayoka A. O., Omotosho E. O. and Odukoya S. A. (2008) “Effect of chronic administration of quinine on the myocardium of mice” Journal of Applied Biomedicine 6, 187 – 193 (published in Czech Republic).
  • 15) Ayoka A. O., Akomolafe R. O., Akanmu M. A., Akinsanmisoye O. S. (2008) “A Review of Medicinal and Research Values of Spondia mombin” African Journal of Biomedical Research 11, 129 – 136 (published in Nigeria).
  • 16) Adewole S. O. and Ayoka A. O. (2009) “Beneficial Role of Quercetin on Developmental Brain of Rats against Oxidative Stress-induced by Lead Poisoning” Pharmacologyonline 2, 1171 – 1184 (published in Italy).
  • 17) Ofusori D. A., Ayoka A. O., Adeeyo O. A. and Adewole S. O. (2009) “Mixture of Kerosene and Xylene: a Contribution to Clearing Agents” International Journal Morphol. 27(1) 211 – 218 (published in Chile).
  • 18) Odukoya S. A., Ofusori D. A., Adeeyo O. A., Ayoka O. A., Abayomi T. A., Ajayi S.
  1. and Falana B. A. (2009) “Comparative biochemical studies of the pregnant and non-pregnant uterine limbs of the frugivorous bat (Eidolon helvum)” Journal of Cell and Animal Biology 3(10) 175 – 178 (published in Kenya).
  • 19) Awe E.O., Makinde J.M and Ayoka A.O (2009) “Evaluation of anti-convulsant property of Russelia equisetiformis (Schlecht and Chain) Journal of Natural Remedies 10(1) (Published in India).
  • 20) Abayomi T. A., Ofusori D. A., Ayoka O. A., Odukoya S. A., Omotoso E. O., Amegor F. O., Ajayi S. A., Ojo G. B. and Oluwayinka O. P. (2009). “A Comparative Histological Study of the Tongue of Rat (Rattus norvegicus), Bat (Eidolon helvum) and Pangolin (Manis tricuspis)” J. Morph Vol. 27 (4) Pg 1111-1119. (Published in Chile).
  • 21) Odukoya S. O. A, Adeeyo O. A, Ofusori D. A, Ayoka O. A, Oluwayinka O. P, Akinyeye A. J, Ojo G.B Ashamu A.E and Babatunde L. S (2009) “Partial Septate Uterus and Tubal Implantation: A Normal Phenomenon in the Eidolon helvum.” Sci Res Essay Vol. 4 (1), pp 013-117. (Published in Kenya).
  • 22) Ajayi S.A., Ofusori D. A., Ojo G. B., Ayoka O.A., Abayomi T. A. and Tijani A. A.

(2011) “The Microstructural Effects of Aqueous Extract of Garcinia Kola (Linn) on the Hippocampus and Cerebellum of Malnourished Mice” Asian Pacific Journal of Tropic Biomedicine (11) 261 – 265. (Published in Asia).

  • 23) Akomolafe, R.O, Bamitale, K.D, Iwalewa, E.O, Adeniyi, O.S, Ayoka, A.O. (2011).

“Effects of Aqueous Anaphe venata Extracts on Fecal pellet Output in Mice.”

International Journal of Biological and Chemical Sciences, 5: 2371-2381. (Cameroon).

  • 24) Nwangwu S., Ofusori D. A., Josiah S., Amegor O. F., Njoya H. and Ayoka A. O (2011) “The Effects of Aqueous and Ethanolic Leaf Extracts of Vernonia amydalina on Some Vital Organs in Adult Wistar Rats” Journal of Cell and Molecular Biology 9 9(1): 75 – 82.
  • 25) Akomolafe, R.O, Adeoshun, I.O, Fakunle J.B, Iwalewa, E.O, Ayoka, A.O, Ajayi, O.E, Odeleye, O.M, Akanji B.O. (2011). “Changes in Some Biochemical Parameters of Kidney Functions of Plasmodium berghei-infected Rats Administered with Some Doses of Artemether” African Journal of Biotechnology, 11: 7119-7127. (Kenya).
  • 26) Ofusori D.A., Komolafe O.A., Adewole S. O., Obuotor E.M., Fakunle J.B. and Ayoka A. O. (2012) “Effects of ethanolic leaf extract of Croton zambesicus (Mull. Arg.) on lipid profile in streptozotocin-induced diabetic rats” Diabetologia Croatica 41(2) 69 – 76.

27) Komolafe O.A., Ofusori D. A., Adewole S. O., Ayoka A. O. and Abiodun A. A. (2012) “Momordica charantia protects against cardiac damage in streptozotocin-induced diabetic wistar rats” Journal of Pharmaceutical and Scientific Innovation 1(3) 32 – 36.

  • 28) Ogunlade O., Ayoka A.O., Akintomide A. O., Ajayi E. A., Ukponmwan O.E. and Ogunlade O.B. (2012) “Gender Differences in electrocardiogram of young adults in South- Western Nigeria” European Journal of Scientific Research 81(1) 26 – 32.

29)Ogunlade O., Ukponmwan O.E., Ayoka A.O., Akintomide A. O. and Ogunlade O.B (2012) “Standard 12-lead electrocardiogram in healthy young adults in South- Western Nigeria” Acta Cardiologica.

  • 30) Ogunlade O., Ayoka A.O., Akintomide A.O, and Ajayi O.E (2013). ″Abnormalities of Electrocardiogram among Apparently Healthy Young Adults in South-Western Nigeria″. European Journal of Scientific Research.135-142.
  • 31) Ayoka A.O., Owolabi R.A, Bamitale S.K, Akomolafe A.O, Aladesanmi J.A and Ukponmwan E.O (2013). ″Effects of Fractionated Extracts and Isolated Pure Compounds of Spondias Mombin (L. anacardiaceae) Leaves on Novelty-Induced Rearing and Grooming Behaviours in Mice″. African Journal of Traditional Complementary and Alternative Medicine 10(5): 244-255 (published in Nigeria).
  • 32) Ayoka A.O., Owolabi R.A, Bamitale S.K, Akomolafe A.O, Aladesanmi J.A and

Ukponmwan E.O (2013). ″Effect of Extracts and Isolated Pure Compounds of Spondias

Mombin (L. anacardiaceae) Leaves on Gross Exploratory Behaviours in Mice″. African Journal of Natural Product and Medicine Vol. 17 pp 81-92 (Published in Nigeria).

  • 33) Komolafe O.A., Ofusori D.A., Adewole O.S., Ayoka A.O. and Ayannuga O.A. (2013)

“Histomophometic Studies of the Aorta, Pulmonary Trunk and Left Ventricle of Streptozotocin-induced Diabetic Wistar Rats Treated with Momordica Charantia Extract” Diabetologia Croatica 42(1) pp 23 – 31.

  • 34) Komolafe O.A., Ofusori D.A., Adewole O.S., Ayoka A.O. and Bejide R. (2013) “Histological and Histochemical Studies of the Aorta and Pulmonary Trunk in

STZ induced Diabetic Wistar Rats Treated with Momordica Charantia” Int. J. Morphol. 31(2): 716 – 723.

  • 35) Ogunlade O., Ayoka A. O and Ajayi O.E (2013) “Heart Survival Card: A Tool for Assessment of Blood Pressure and Management of Hypertension” European Journal of Scientific Research 103(4): 516 – 520.
  • 36) Akomolafe R.O., Adeosun S.I, Fakunle J.B., Iwalewa E.O., Ayoka A.O., Ajayi O.E., Odeleye O.M and Akanji B.O (2013). “Effects of artemether on biochemical markers of liver function in Plasmodium berghei-infected and non-infected rats” African Journal of Biotechnology 12(11) 1275- 1287 (Published in Kenya).
  • 37) Okunlola A.I., Okunlola C.K., Okani C.O., Adewole S.O., Ofusori D.A., Komolafe O.A., Ojo S.K., Bejide R.A., Ayoka A.O and Ojewole J.A.O. (2014) “Histological studies on the retina and cerebellum of Wistar rats treated with Arteether” Journal of Morphol. Sci., 31(1): 28 – 32. (Published in Chile).
  • 38) Ayoka A. O., Adeloye A. O., Aladesanmi A. J. and Ukponmwan O. E. (2014) “Isolation of Three Compounds from the Leaves of Spondias Mombin” Nigerian Journal of Natural Products and Medicine Vol 18. pp 28 – 32 (Published in Nigeria).
  • 39) Ayoka A.O., Okonji R.E., Ofusori D.A., Komolafe O.A., Bamitale K.D.S and Fakunle J.B. (2014) “Effect of Xylopia aethiopica, Fiscus mucuso and Anthocleista vogelli Extracts on some Biochemical Parameters Following Ethanol-induced Toxicity” British Journal of Medical & Medical Research. 4(14): 2705 – 2712.
  • 40) Ayoka A.O., Ogunlade O., Akintomide A.O., Akomolafe R.O and Ajayi O.E. (2014) “Normal limits of Electrocardiogram and Cut-Off values for left Ventricular Hypertrophy in Young Adult Nigerians” Nigerian Journal of Physiological Sciences. 29: pp 63 – 66. (Published in Nigeria).
  • 41) Ojoawo A.O., Awogboro O. I., Ayoka A.O., Adeniran S.A. and Ogunlade A. (2015) “Comparison between selected anthropometric indices of patients with cancer and age matched apparently healthy individual” Journal of the Romanian Sports Medicine Society. 11 (2): 2541 – 2546.
  • 42) Ogunlade O., Ayoka A. O., Akintomide A., Akomolafe R.O., Akinsomisoye O.S., and

Oyebola D.D. (2015) “Non-Invasive Assessment of Cardiac Autonomic Functions in Healthy Young Adults in Ile – Ife, South-Western Nigeria” International Journal of Clinical Cardiology. 2:036.

  • 43) Ogunlade O., Asafa M.A., Ayoka A. O., Akomolafe R.O and Akintomide A.O. (2015) “Effects of age and sex on autonomic cardiovascular indices among apparently healthy young adults” Scholars Academic Journal of Biosciences. 3(12): 1040 – 1043.
  • 44) Ogunlade O., Ayoka A. O., Akomolafe R.O., Akinsomisoye O.S., Irinoye A.I., Ajao A and Asafa M.A. (2015) “The role of Electrocardiogram in the diagnosis of dextrocardia with mirror image atrial arrangement and ventricular position in a young adult Nigerian in Ile – Ife: a case report” Journal of Medical Case Reports”. Journal of Medical Case Report. 9: 222.
  • 45) Asafa M.A., Ogunlade O., Osasogie O.E., Ayoka A.O. (2016) “Evaluation of electrocardiogram as a biological signal for sex verification among fresh undergraduates in a Nigerian tertiary institution”. Nigerian Journal of Cardiology.13:103-6.
  • 46) Ayoka A.O., Ademoye A.K., Imafidon E.C., Ojo O.E., Oladele A.A. (2016) “Aqueous

Extract of Allium sativum (Linn.) Bulbs Ameliorated Pituitary-Testicular Injury and Dysfunction in Wistar Rats with Pb-Induced Reproductive Disturbances”. Open Access Maced J Med Sci. 4(2):200-212.

  • 47) Ogunlade O., Asafa M.A., Ayoka A.O., Akintomide A.O. (2016) “Association between body anthropometric parameters and indices of cardiac autonomic function among apparently healthy young adults”. Arch Med Health Sci. 4:26-9.
  • 48) Ayoka A.O., Ojo O.E., Imafidon E.C.,Ademoye K.A., Oladele A.A. (2016) “Neuroendocrine effects of aqueous extract of Amaranthus viridis (Linn.) leaf in male Wistar rat model of cyclophosphamide-induced reproductive toxicity”. Toxicology Reports 3: 608– 619.
  • 49) Bamidele O., Kolawole1 J. T., Ayoka A. O., Babatunde L. D., Onaseso O. O. and Adedeji G. T. (2017) “Wound Healing Potentials of Aqueous Leaf Extract of Mangifera indica L.

in Wistar Rats”. Journal of Complementary and Alternative Medical Research. 2(4): 1-11.

  • 50) Osuntokun O.S., Olayiwola G., Oladele A., Ola I. and Ayoka A.O. (2017). “Chronic administration of gabapentin and a gabapentin-carbamazepine combination reversibly suppress testicular function in male Wister rats (Rattus norvegicus)”. Pathophysiology. 24: 63 – 69.
  • 51) Bamidele O., Otabor E. O., Arokoyo D. S., Babatunde L. D., Adeleye G. S. and Ayoka A.O. (2017) “Effects of Ethanol Extract of Moringa oleifera (Lam)Leaves on Nicotineinduced Changes in Haematological Parameters in Male Wistar Rats (Rattus norvegicus)” European Journal of Medicinal Plants. 18(4): 1-11.
  • 52) Ojo A.O., Oludapo O., Onaseso O.O., Adedayo L.D., Oluranti O.I., Emmanuel O.T., Bamidele O., Ayoka A.O. (2020). “Aspilia africana Altered Haematological Parameters and Plasma Electrolytes in Rats (Rattus norvengicus)”. Haya Saudi J Life Sci. 5(5): 58-64.
  • 53) Adedayo L, Offor G, Jolayemi O, Ojo G, Bamidele O, Ojo A, Emmanuel T, Aitokhuehi N, Onasanwo S and Ayoka A. (2021). “Aripiprazole ameliorates scopolamine-induced amnesia in mice”. Journal of Pharmacy and Bioresources 18(1): 12-24.
  • 54) Osuntokun O.S., Akingboye B.G., Olayiwola G., Abayomi T.A. and Ayoka A.O (2021) “The impairment of motor coordination following chronic carbamazepine-levetiracetam combination treatment with evidence of corticocerebellar toxicity in male Wistar rats.” Brain Research, 1767, 147565:1-8.

55) Taiwo O.O., Akano O.P., Adeoye A.D., Odunkoya S.O.A and Ayoka A.O (2021). “Effects of Ethanol Extract of secamone afzelii (Schult) K.Schum (Asclepiadceae) Leaves on Aluminum Chloride-induced Reproductive Toxicity in Male Wistar Rats”. Journal of Krishna Institute of Medical Sciences University 10(2):1-12.

  • 56) Osuntokun O.S., Oladokun O.O., Adedokun K.I., Atere T.G., Olayiwola G., Ayoka A.O. (2021). “Hepato-toxicological and lipid profile of male Wistar rats following chronic carbamazepine, gabapentin, and carbamazepine-gabapentin adjunctive treatment”. Research Journal of Health Sciences 9(3):289-298.
  • 57) Ojo, A. O., Ekomaye, O. H., Owoade, O. M., Onaseso, O. O., Adedayo, L. D., Oluranti, O. I., Timothy, E. O., Ayoka, A. (2021). “The effect of ginger (Zingiber officinale) feed on cardiac biomarker in medium-dose isoproterenol-induced myocardial toxicity”. Avicenna journal of phytomedicine, 11(1), 1–10.